(Peer-reviewed articles)

Transport and uptake studies

Bartholomé K, Rius M, Letschert K, Keller D, Timmer J, Keppler D. Kopplow K, Letschert K, Konig J, Walter B, Keppler D.
Data-Based Mathematical Modeling of Vectorial Transport across Double-Transfected Polarized Cells.
Drug Metab Dispos. 2007 Sep;35(9):1476-81.
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Kopplow K, Letschert K, Konig J, Walter B, Keppler D.
Human hepatobiliary transport of organic anions analyzed by quadruple-transfected cells.
Mol Pharmacol. 2005 Oct;68(4):1031-8. Epub 2005 Jul 26.
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Letschert K, Faulstich H, Keller D, Keppler D.
Molecular characterization and inhibition of amanitin uptake into human hepatocytes.
Toxicol Sci. 2006 May;91(1):140-9. Epub 2006 Feb 22.
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Letschert K, Komatsu M, Hummel-Eisenbeiss J, Keppler D.
Vectorial transport of the peptide CCK-8 by double-transfected MDCKII cells stably expressing the organic anion transporter OATP1B3 (OATP8) and the export pump ABCC2.
J Pharmacol Exp Ther. 2005 May;313(2):549-56. Epub 2005 Jan 21.
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Mettlen M, Platek A, Van Der Smissen P, Carpentier S, Amyere M, Lanzetti L, de Diesbach P, Tyteca D, Courtoy PJ.
Src triggers circular ruffling and macropinocytosis at the apical surface of polarized MDCK cells.
Traffic. 2006 May;7(5):589-603.
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Nies AT, Herrmann E, Brom M, Keppler D.
Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic cation transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1).
Naunyn Schmiedebergs Arch Pharmacol. 2008 Feb;376(6):449-61. Epub 2007 Dec 19.
Key words: Vectorial transport, MDCKII cells, berberine, OCT1, SLC22A1, ABCB1
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Migration and invasion studies

Bartling B, Hofmann HS, Weigle B, Silber RE, Simm A.
Down-regulation of the receptor for advanced glycation end-products (RAGE) supports non-small cell lung carcinoma.
Carcinogenesis. 2005 Feb;26(2):293-301. Epub 2004 Nov 11.
Key words: Migration, Lung carcinoma, RAGE
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Dittmer A, Vetter M, Schunke D, Span PN, Sweep F, Thomssen C, Dittmer J.
Parathyroid hormone-related protein regulates tumor-relevant genes in breast cancer cells.
J Biol Chem. 2006 May 26;281(21):14563-72. Epub 2006 Mar 21.
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Hiscox S, Jiang WG, Obermeier K, Taylor K, Morgan L, Burmi R, Barrow D, Nicholson RI.
Tamoxifen resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of beta-catenin phosphorylation.
Int J Cancer. 2006 Jan 15;118(2):290-301.
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Hutcheson IR, Knowlden JM, Hiscox SE, Barrow D, Gee JM, Robertson JF, Ellis IO, Nicholson RI.
Heregulin beta1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells.
Breast Cancer Res. 2007;9(4):R50.
Key words: Invasion, Herregulin beta 1, MCF-7, gefitinib
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Kitzing TM, Sahadevan AS, Brandt DT, Knieling H, Hannemann S, Fackler OT, Großhans J, Grosse R.
Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion.
Genes Dev. 2007 Jun 15;21(12):1478-1483.
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Luo XG, Ding Y, Zhou QF, Ye L, Wang SZ, Xi T.
SET and MYND domain-containing protein 3 decreases sensitivity to dexamethasone and stimulates cell adhesion and migration in NIH3T3 cells.
J Biosci Bioeng. 2007 May;103(5):444-50.
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Mandic R, Ludwig T, Oberleithner H, Werner JA.
Evaluation of head and neck squamous cell carcinoma invasiveness by the electrical resistance breakdown assay.
Clin Exp Metastasis. 2004;21(8):699-704.
Key Words: TEER, invasion, MDCK-C7 cells, HNSCC cells, MMP, TIMP
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Oudhoff MJ, Bolscher JG, Nazmi K, Kalay H, van't Hof W, Nieuw  Am
Histatins are the major wound-closure stimulating factors in human saliva as identified in a cell culture assay.
FASEB J. 2008 Jul 23. [Epub ahead of print]
Key words: Migration, wound closure, HO-1-N-1 cells, Saliva, Histatin, Hst1, Hst2
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Saidi H, Magri G, Carbonneil C, Nasreddine N, Requena M, Belec L.
IFN-gamma-activated monocytes weakly produce HIV-1 but induce the recruitment of HIV-sensitive T cells and enhance the viral production by these recruited T cells.
J Leukoc Biol. 2007 Mar;81(3):642-53. Epub 2006 Sep 13.
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Thevenard J, Floquet N, Ramont L, Prost E, Nuzillard JM, Dauchez M, Yezid H, Alix AJ, Maquart FX, Monboisse JC, Brassart-Pasco S.
Structural and antitumor properties of the YSNSG cyclopeptide derived from tumstatin.
Chem Biol. 2006 Dec;13(12):1307-15.
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Co-Culture

Fong SP, Tsang KS, Chan AB, Lu G, Poon WS, Li K, Baum LW, Ng HK.
Trophism of neural progenitor cells to embryonic stem cells: Neural induction and transplantation in a mouse ischemic stroke model.
J Neurosci Res. 2007 Jul;85(9):1851-62.
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Infection studies

Hoek KL, Duffy LB, Cassell GH, Dai Y, Atkinson TP.
A role for the Mycoplasma pneumoniae adhesin P1 in interleukin (IL)-4 synthesis and release from rodent mast cells.
Microb Pathog. 2005 Oct;39(4):149-58.
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Tissue reconstruction, 3D cultures

Muehlfriedel S, Knebel G.
The establishment of in vivo-like tissue culture conditions in ThinCert™ tissue culture products.
BioTechniques®. 2007 December;43(6):812-813.
Key words: Tissue reconstruction, skin-models, air-lift-culture.
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Smith LE, Rimmer S, MacNeil S.
Examination of the effects of poly(N-vinylpyrrolidinone) hydrogels in direct and indirect contact with cells.
Biomaterials. 2006 May;27(14):2806-12. Epub 2006 Jan 19.
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